ゼミ / Seminars 2023

論文紹介 / Article presentation

Date Presenter Article
2023/12/15 Momo Matsushima Sun P, Jia K, Zheng C, Zhu X, Li J, He L, Siwko S, Xue F, Liu M, Luo J. Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells. J Cell Physiol. 2019; 234: 10855-10867.
2023/12/07 Chika Ishida Stanley A, Tichy ED, Kocan J, Roberts DW, Shore EM, Mourkioti F. Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva. NPJ Regen Med. 2022; 7: 5.
2023/12/01 Yuri Hirabayashi Nagao Y, Yokoi A, Yoshida K, Sugiyama M, Watanabe E, Nakamura K, Kitagawa M, Asano-Inami E, Koya Y, Yoshihara M, Tamauchi S, Shimizu Y, Ikeda Y, Yoshikawa N, Kato T, Yamamoto Y, Kajiyama H. Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma. Pharmacol Res. 2023; 189: 106693.
2023/11/24 Yuri Hirabayashi 平林ゆり. 修士論文中間発表会 (予演).
2023/11/17 Chihaya Kimura Okita K, Hikiji H, Koga A, Nagai-Yoshioka Y, Yamasaki R, Mitsugi S, Fujii W, Ariyoshi W. Ascorbic acid enhances chondrocyte differentiation of ATDC5 by accelerating insulin receptor signaling. Cell Biol Int. 2023; 47: 1737-1748.
2023/11/09 Machi Yamamoto Skrzypek K, Nieszporek A, Badyra B, Lasota M, Majka M. Enhancement of myogenic differentiation and inhibition of rhabdomyosarcoma progression by miR-28-3p and miR-193a-5p regulated by SNAIL. Mol Ther Nucleic Acids. 2021; 24: 888-904.
2023/11/02 Tomohide Takaya Yu Z, Yang W, He X, Chen C, Li W, Zhao L, Liu L, Liu J, Xie L, Zhang Y, Zheng J. Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches. Blood. 2022; 139: 1529-1540.
2023/10/26 Chihaya Kimura Ju L, Hu P, Chen P, Xue X, Li Z, He F, Qiu Z, Cheng J, Huang F. Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/Akt/NF-κB pathway. Biomed Pharmacother. 2020; 129: 110471.
2023/10/19 Yuri Hirabayashi Yang Q, Bariani MV, Falahati A, Khosh A, Lastra RR, Siblini H, Boyer TG, Al-Hendy A. The functional role and regulatory mechanism of bromodomain-containing protein 9 in human uterine leiomyosarcoma. Cells. 2022; 11: 2160.
2023/10/13 Machi Yamamoto Nakahata K, Simons BW, Pozzo E, Shuck R, Kurenbekova L, Prudowsky Z, Dholakia K, Coarfa C, Patel TD, Donehower LA, Yustein JT. K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications. Dis Model Mech. 2022; 15: dmm049004.
2023/10/10 Tomohide Takaya Hino K, Zhao C, Horigome K, Nishio M, Okanishi Y, Nagata S, Komura S, Yamada Y, Toguchida J, Ohta A, Ikeya M. An mTOR signaling modulator suppressed heterotopic ossification of fibrodysplasia ossificans progressiva. Stem Cell Reports. 2018; 11: 1106-1119.
2023/09/29 Chihaya Kimura 木村智勇. 研究紹介.
2023/09/22 Yuri Hirabayashi 平林ゆり. 研究紹介.
2023/09/15 Machi Yamamoto 山本万智. 研究紹介.
2023/09/08 Tomohide Takaya 高谷智英. 研究紹介.
2023/09/1 Tomohide Takaya 高谷智英. 研究紹介.
2023/07/28 Chihaya Kimura Vis AMK, de Wildt BWM, Ito K, Hofmann S. A dialysis medium refreshment cell culture set-up for an osteoblast-osteoclast coculture. Biotechnol Bioeng. 2023; 120: 1120-1132.
2023/07/21 Yuri Hirabayashi Yoshida K, Yokoi A, Yamamoto T, Hayashi Y, Nakayama J, Yokoi T, Yoshida H, Kato T, Kajiyama H, Yamamoto Y. Aberrant activation of cell-cycle-related kinases and the potential therapeutic impact of PLK1 or CHEK1 inhibition in uterine leiomyosarcoma. Clin Cancer Res. 2022; 28: 2147-2159.
2023/07/14 Machi Yamamoto Liu C, Zhang L, Cui W, Du J, Li Z, Pang Y, Liu Q, Shang H, Meng L, Li W, Song L, Wang P, Xie Y, Wang Y, Liu Y, Hu J, Zhang W, Li F. Epigenetically upregulated GEFT-derived invasion and metastasis of rhabdomyosarcoma via epithelial mesenchymal transition promoted by the Rac1/Cdc42-PAK signalling pathway. EBioMedicine. 2019; 50: 122-134.
2023/07/07 Chihaya Kimura 木村智勇. 修士院試 (予演).
2023/07/04 Chihaya Kimura Batoon L, Millard SM, Raggatt LJ, Wu AC, Kaur S, Sun LWH, Williams K, Sandrock C, Ng PY, Irvine KM, Bartnikowski M, Glatt V, Pavlos NJ, Pettit AR. Osteal macrophages support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. J Bone Miner Res. 2021; 36: 2214-2228.
2023/06/23 Tomohide Takaya Ebner JK, Konig GM, Kostenis E, Siegert P, Aktories K, Orth JHC. Activation of Gq signaling by Pasteurella multocida toxin inhibits the osteoblastogenic-like actions of activin A in C2C12 myoblasts, a cell model of fibrodysplasia ossificans progressiva. Bone. 2019; 127: 592-601.
2023/06/02 Chihaya Kimura 木村智勇, 高谷智英. 骨芽細胞と前破骨細胞の共培養系における骨形成型オリゴ DNA の作用. 第23回日本抗加齢医学会 (予演).
2023/05/26 Yuri Hirabayashi Szabo K, Varga D, Vegh AG, Liu N, Xiao X, Xu L, Dux L, Erdelyi M, Rovo L, Keller-Pinter A. Syndecan-4 affects myogenesis via Rac1-mediated actin remodeling and exhibits copy-number amplification and increased expression in human rhabdomyosarcoma tumors. Cell Mol Life Sci. 2022; 79: 122.
2023/05/19 Machi Yamamoto Sims D, Maranyane HM, Damerell V, Govender D, Isaacs AW, Peres J, Prince S. The c-Myc/AKT1/TBX3 axis is important to target in the treatment of embryonal rhabdomyosarcoma. Cancers. 2020; 12: 501.
2023/05/12 Tomohide Takaya de la Hoz R, Diban N, Berciano MT, San Emeterio C, Urtiaga A, Lafarga M, Rodriguez-Rey JC, Tapia, O. Coaxial synthesis of PEI-based nanocarriers of encapsulated RNA-therapeutics to specifically target muscle cells. Biomolecules. 2023; 12: 1012.
2023/04/28 Chihaya Kimura Uenaka M, Yamashita E, Kikuta J, Morimoto A, Ao T, Mizuno H, Furuya M, Hasegawa T, Tsukazaki H, Sudo T, Nishikawa K, Okuzaki D, Motooka D, Kosaka N, Sugihara F, Boettger T, Braun T, Ochiya T, Ishii M. Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo. Nat Commun. 2022; 13: 1066.
2023/04/21 Yuri Hirabayashi Suzuki T, Dai T, Ono M, Kojima J, Sasaki T, Fujiwara H, Kuji N, Nishi H. Pivotal role of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) in uterine leiomyoma. Biomolecules. 2023; 13: 193.
2023/04/14 Machi Yamamoto Knopp P, Krom YD, Banerji CR, Panamarova M, Moyle LA, den Hamer B, van der Maarel SM, Zammit PS. DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis. J Cell Sci. 2016; 129: 3816-3831.
2023/04/07 Tomohide Takaya Philippou S, Mastroyiannopoulos NP, Makrides N, Lederer CW, Kleanthous M, Phylactou LA. Selection and identification of skeletal-muscle-targeted RNA aptamers. Mol Ther Nucleic Acids. 2018; 10: 199-214.
2023/02/10 Chihaya Kimura Xiong L, Zhao K, Cao Y, Guo HH, Pan JX, Yang X, Ren X, Mei L, Xiong WC. Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency. PLoS Biol. 2020; 18: e3000731.
2023/02/03 Mana Miyoshi 三好愛. 筋形成型オリゴ DNA による抗動脈硬化作用の検討. 修士論文発表会 (予演).
Kamino Morioka 森岡一乃. 筋形成型オリゴ DNA による抗肥満作用の検討. 修士論文発表会 (予演).
2023/01/20 Machi Yamamoto Masteika IF, Sathya A, Homma S, Miller BM, Boyce FM, Miller JB. Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, γH2AX accumulation, and Bax/Bak-dependence. Biol Open. 2022; 11: bio059145.
2023/01/19 Tomohide Takaya Sun H, Huang L, Liang P, Tang Y, Chen C, Chen H, Lin X, Luo Z, Li Y, Jiang B, Xiao X. Nucleolin regulates the proliferation of vascular smooth muscle cells in atherosclerotic via Aurora B. J Cell Mol Med. 2021; 25: 751-762.