| Date |
Presenter |
Article |
| 2024/12/19 |
Koyuki Naka |
Sun L, Meng H, Liu T, Zhao Q, Xia M, Zhao Z, Qian Y, Cui H, Zhong X, Chai K, Tian Y, Sun Y, Zhu B, Di J, Shui G, Zhang L, Zheng J, Guo S, Liu Y. Nucleolin malonylation as a nuclear-cytosol signal exchange mechanism to drive cell proliferation in hepatocarcinoma by enhancing AKT translation. J Biol Chem. 2024; 300: 107785. |
| 2024/12/13 |
Yoshihiro Saitoh |
Huttner SS, Henze H, Elster D, Koch P, Anderer U, von Eyss B, von Maltzahn J. A dysfunctional miR-1-TRPS1-MYOG axis drives ERMS by suppressing terminal myogenic differentiation. Mol Ther. 2023; 31: 2612-2632. |
| 2024/12/06 |
Momo Matsushima |
Park JS, Kim M, Song NJ, Kim JH, Seo D, Lee JH, Jung SM, Lee JY, Lee J, Lee YS, Park KW, Park SH. A reciprocal role of the Smad4-Taz axis in osteogenesis and adipogenesis of mesenchymal stem cells. Stem Cells. 2019; 37: 368-381. |
| 2024/11/29 |
Chika Ishida |
Burdick LN, DelVichio AH, Hanson LR, Griffith BB, Bouchard KR, Hunter JW, Goldhamer DJ. Sex as a critical variable in basic and pre-clinical studies of fibrodysplasia ossificans progressiva. Biomolecules. 2024; 14: 177. |
| 2024/11/22 |
Chihaya Kimura |
木村智勇. 修士論文中間発表会 (予演). |
| 2024/11/15 |
Yuri Hirabayashi |
Lamora A, Talbot J, Bougras G, Amiaud J, Leduc M, Chesneau J, Taurelle J, Stresing V, Le Deley MC, Heymann MF, Heymann D, Redini F, Verrecchia F.Overexpression of Smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma. Clin Cancer Res. 2014; 20: 5097-5112. |
| 2024/11/06 |
Momo Matsushima |
Zhu J, Mo L, Li M, Wang Y, Zhang G, Tao Z, Liao X, Du M, He H. Long non-coding RNA Snhg15 promotes preosteoblast proliferation by interacting with and stabilizing nucleolin. Biochim Biophys Acta Mol Cell Res. 2024; 1871: 119847. |
| 2024/10/31 |
Chika Ishida |
Tu B, Li J, Sun Z, Zhang T, Liu H, Yuan F, Fan C. Macrophage-derived TGF-β and VEGF promote the progression of trauma-induced heterotopic ossification. Inflammation. 2023; 46: 202-216. |
| 2024/10/29 |
Chihaya Kimura |
Yu C, Peall IW, Pham SH, Okolicsanyi RK, Griffiths LR, Haupt LM. Syndecan-1 facilitates the human mesenchymal stem cell osteo-adipogenic balance. Int J Mol Sci. 2020; 21: 3884. |
| 2024/10/18 |
Yuri Hirabayashi |
Ohba T, Cates JM, Cole HA, Slosky DA, Haro H, Ando T, Schwartz HS, Schoenecker JG. Autocrine VEGF/VEGFR1 signaling in a subpopulation of cells associates with aggressive osteosarcoma. Mol Cancer Res. 2014; 12: 1100-1111. |
| 2024/10/04 |
Momo Matsushima |
松島もも. 研究紹介. |
| 2024/10/03 |
Chika Ishida |
石田智香. 研究紹介. |
| 2024/09/20 |
Chihaya Kimura |
木村智勇. 研究紹介. |
| 2024/09/12 |
Yuri Hirabayashi |
平林ゆり. 研究紹介. |
| 2024/09/06 |
Tomohide Takaya |
高谷智英. 研究紹介. |
| 2024/07/12 |
Tomohide Takaya |
高谷智英, 山本万智. 抗ヌクレオリンアプタマー iSN04 は異種移植マウスにおける胎児型横紋筋肉腫の増殖を抑制する. 日本核酸医薬学会第9回年会 (予演). |
| Chihaya Kimura |
木村智勇, 高谷智英. 骨形成型オリゴ DNA はインスリン依存的に軟骨分化を促進する. 日本核酸医薬学会第9回年会 (予演). |
| Chika Ishida |
石田智香, 高谷智英. 抗ヌクレオリンアプタマー iSN04 は BMP2 による筋分化阻害を回復する. 日本核酸医薬学会第9回年会 (予演). |
| Momo Matsushima |
松島もも, 高谷智英. 抗ヌクレオリンアプタマー iSN04 は BMP2 依存的な骨分化を抑制する. 日本核酸医薬学会第9回年会 (予演). |
| 2024/07/05 |
Chika Ishida |
石田智香. 修士院試 (予演). |
| Momo Matsushima |
松島もも. 修士院試 (予演). |
| 2024/06/21 |
Momo Matsushima |
Liu ZZ, Hong CG, Hu WB, Chen ML, Duan R, Li HM, Yue T, Cao J, Wang ZX, Chen CY, Hu XK, Wu B, Liu HM, Tan YJ, Liu JH, Luo ZW, Zhang Y, Rao SS, Luo MJ, Yin H, Wang YY, Xia K, Xu L, Tang SY, Hu RG, Xie H. Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. Autophagy. 2021; 17: 2766-2782. |
| 2024/06/14 |
Chika Ishida |
Wang H, Zhang Q, Kaplan FS, Pignolo RJ. Clearance of senescent cells from injured muscle abrogates heterotopic ossification in mouse models of fibrodysplasia ossificans progressiva. J Bone Miner Res. 2022; 37: 95-107. |
| 2024/06/07 |
Chihaya Kimura |
Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI. Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. J Biol Chem. 2013; 288: 9924-9932. |
| 2024/05/31 |
Yuri Hirabayashi |
Omori K, Otani S, Date Y, Ueno T, Ito T, Umeda M, Ito K. C/ebpα represses the oncogenic Runx3-Myc axis in p53-deficient osteosarcoma development. Oncogene. 2023; 42: 2485-2494. |
| 2024/05/24 |
Tomohide Takaya |
Wang L, Yu Y, Ni S, Li D, Liu J, Xie D, Chu HY, Ren Q, Zhong C, Zhang N, Li N, Sun M, Zhang ZK, Zhuo Z, Zhang H, Zhang S, Li M, Xia W, Zhang Z, Chen L, Shang P, Pan X, Lu A, Zhang BT, Zhang G. Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice. Theranostics. 2022; 12: 5645-5674. |
| 2024/05/17 |
Momo Matsushima |
Lin Z, He H, Wang M, Liang J. MicroRNA-130a controls bone marrow mesenchymal stem cell differentiation towards the osteoblastic and adipogenic fate. Cell Prolif. 2019; 52: e12655. |
| 2024/05/10 |
Chika Ishida |
Aykul S, Huang L, Wang L, Das NM, Reisman S, Ray Y, Zhang Q, Rothman N, Nannuru KC, Kamat V, Brydges S, Troncone L, Johnsen L, Yu PB, Fazio S, Lees-Shepard J, Schutz K, Murphy AJ, Economides AN, Idone V, Hatsell SJ. Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1. 2022; 132: e153792. |
| 2024/04/26 |
Chihaya Kimura |
Caron MMJ, Eveque M, Cillero-Pastor B, Heeren RMA, Housmans B, Derks K, Cremers A, Peffers MJ, van Rhijn LW, van den Akker G, Welting TJM. Sox9 determines translational capacity during early chondrogenic differentiation of ATDC5 cells by regulating expression of ribosome biogenesis factors and ribosomal proteins. Front Cell Dev Biol. 2021; 9: 686096. |
| 2024/04/19 |
Yuri Hirabayashi |
Hemming ML, Fan C, Raut CP, Demetri GD, Armstrong SA, Sicinska E, George S. Oncogenic gene-expression programs in leiomyosarcoma and characterization of conventional, inflammatory, and uterogenic subtypes. Mol Cancer Res. 2020; 18: 1302-1314. |
| 2024/04/12 |
Tomohide Takaya |
Xia Y, Cheng X, Nilsson T, Zhang M, Zhao G, Inuzuka T, Teng Y, Li Y, Anderson DE, Holdorf M, Liang TJ. Nucleolin binds to and regulates transcription of hepatitis B virus covalently closed circular DNA minichromosome. Proc Natl Acad Sci USA. 2023; 120: e2306390120. |
| 2024/03/15 |
Yuri Hirabayashi |
平林ゆり, 高谷智英. 筋形成型オリゴ DNA の抗子宮平滑筋肉腫作用の検討. 日本農芸化学会2024年度大会 (予演). |
| Chihaya Kimura |
木村智勇, 高谷智英. 骨細胞、破骨細胞、軟骨細胞分化における骨形成型オリゴ DNA の作用. 日本農芸化学会2024年度大会 (予演). |
| Chika Ishida |
石田智香, 山本万智, 高谷智英. 筋形成型オリゴ DNA は BMP2 による筋分化の阻害を回復する. 日本農芸化学会2024年度大会 (予演). |
| Momo Matsushima |
松島もも, 木村智勇, 高谷智英. 筋形成型オリゴ DNA は BMP2 依存的な骨芽細胞の分化を阻害する. 日本農芸化学会2024年度大会 (予演). |
| 2024/02/22 |
Momo Matsushima |
Gao J, Wang H, Shen J, Liu X, Zhu X, Huang C, Li G, Sun Y, Liu Z, Sun YE, Liu H. Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells. J Cell Physiol. 2023; . |
| 2024/02/16 |
Chika Ishida |
Katagiri T, Tsukamoto S, Kuratani M, Tsuji S, Nakamura K, Ohte S, Kawaguchi Y, Takaishi K. A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. Nat Commun. 2023; 14: 2960. |
| 2024/02/02 |
Machi Yamamoto |
山本万智. マウスモデルを用いた筋形成型オリゴ DNA の抗横紋筋肉腫作用の研究. 修士論文発表会 (予演). |
| 2024/01/26 |
Chihaya Kimura |
木村智勇. 破骨細胞と軟骨細胞の分化における骨形成型オリゴ DNA の作用. 専攻研究論文発表会 (予演). |
| 2024/01/19 |
Yuri Hirabayashi |
Kodama M, Shimura H, Tien JC, Newberg JY, Kodama T, Wei Z, Rangel R, Yoshihara K, Kuruma A, Nakae A, Hashimoto K, Sawada K, Kimura T, Jenkins NA, Copeland NG. Sleeping Beauty transposon mutagenesis identifies genes driving the initiation and metastasis of uterine leiomyosarcoma. Cancer Res. 2021; 81: 5413-5424. |
| 2024/01/11 |
Tomohide Takaya |
Sun S, Liu H, Hu Y, Wang Y, Zhao M, Yuan Y, Han Y, Jing Y, Cui J, Ren X, Chen X, Su J. Selection and identification of a novel ssDNA aptamer targeting human skeletal muscle. Bioact Mater. 2023; 20: 166-178. |
