分子細胞機能学研究室

ホーム研究実験業績メンバーリンク

論文紹介 / Article presentation

Date	Presenter	Article
2021/12/22	Machi Yamamoto	Sosa P, Alcalde-Estevez E, Asenjo-Bueno A, Plaza P, Carrillo-Lopez N, Olmos G, Lopez-Ongil S, Ruiz-Torres MP. Aging-related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle. J Cachexia Sarcopenia Muscle. 2021; 12: 1266-1279.
2021/12/09	Naoki Nohira	Lavoie RR, Gargollo PC, Ahmed ME, Kim Y, Baer E, Phelps DA, Charlesworth CM, Madden BJ, Wang L, Houghton PJ, Cheville J, Dong H, Granberg CF, Lucien F. Surfaceome profiling of rhabdomyosarcoma reveals B7-H3 as a mediator of immune evasion. Cancers. 2021; 13: 4528.
2021/12/02	Rena Ikeda	Maria S, Samsonraj RM, Munmun F, Glas J, Silvestros M, Kotlarczyk MP, Rylands R, Dudakovic A, van Wijnen AJ, Enderby LT, Lassila H, Dodda B, Davis VL, Balk J, Burow M, Bunnell BA, Witt-Enderby PA. Biological effects of melatonin on osteoblast/osteoclast cocultures, bone, and quality of life: Implications of a role for MT2 melatonin receptors, MEK1/2, and MEK5 in melatonin-mediated osteoblastogenesis. J Pineal Res. 2018; 64: e12465.
2021/11/25	Machi Yamamoto	Mariero LH, Torp MK, Heiestad CM, Baysa A, Li Y, Valen G, Vaage J, Stenslokken KO. Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation. Br J Pharmacol. 2019; 176: 4360-4372.
2021/11/18	Mana Miyoshi	三好愛. 修士論文中間発表会 (予演)
	Kamino Morioka	森岡一乃. 修士論文中間発表会 (予演)
2021/11/11	Yuma Nihashi	二橋佑磨. 博士論文予備審査 (予演)
2021/11/04	Tomohide Takaya	高谷智英. 研究紹介.
2021/10/28	Naoki Nohira	Rammal G, Fahs A, Kobeissy F, Mechref Y, Zhao J, Zhu R, Diab-Assaf M, Saab R, Ghayad SE. Proteomic profiling of rhabdomyosarcoma-derived exosomes yield insights into their functional role in paracrine signaling. J Proteome Res. 2019; 18: 3567-3579.
2021/10/21	Kamino Morioka	Bagchi DP, NishiiA, Li Z, DelProposto JB, Corsa CA, Mori H, Hardij J, Learman BS, Lumeng CN, MacDougald OA. Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells. Mol Metab. 2020; 42: 101078.
2021/10/14	Rena Ikeda	Nakao Y, Fukuda T, Zhang Q, Sanui T, Shinjo T, Kou X, Chen C, Liu D, Watanabe Y, Hayashi C, Yamato H, Yotsumoto K, Tanaka U, Taketomi T, Uchiumi T, Le AD, Shi S, Nishimura F. Exosomes from TNF-alpha-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss. Acta Biomater. 2021; 122: 306-324.
2021/10/07	Mana Miyoshi	Riascos-Bernal DF, Chinnasamy P, Gross JN, Almonte V, Egana-Gorrono L, Parikh D, Jayakumar S, Guo L, Sibinga NES. Inhibition of smooth muscle β-catenin hinders neointima formation after vascular injury. Arterioscler Thromb Vasc Biol. 2017; 37: 879-888.
2021/09/30	Yuma Nihashi	Fang L, Wang KK, Huang Q, Cheng F, Huang F, Liu WW. Nucleolin mediates LPS-induced expression of inflammatory mediators and activation of signaling pathways. Curr Med Sci. 2020; 40: 646-653.
2021/09/10	Mana Miyoshi	三好愛, 二橋佑磨, 梅澤公二, 下里剛士, 高谷智英. 筋形成型オリゴ DNA による平滑筋細胞の分化制御. 日本農芸化学会中部支部第190回支部例会 (予演).
	Kamino Morioka	森岡一乃, 三谷塁一, 梅澤公二, 下里剛士, 高谷智英. 筋形成型オリゴ DNA は脂肪前駆細胞の分化と炎症反応を抑制する. 日本農芸化学会中部支部第190回支部例会 (予演).
	Naoki Norhia	野平直樹, 二橋佑磨, 下里剛士, 高谷智英. ヒト胎児型横紋筋肉腫細胞における筋形成型オリゴ DNA の作用. 日本農芸化学会中部支部第190回支部例会 (予演).
	Machi Yamamoto	山本万智, 三谷塁一, 高谷智英. 筋形成型オリゴ DNA は筋芽細胞の NF-κB 依存的な炎症反応を抑制する. 日本農芸化学会中部支部第190回支部例会 (予演).
2021/07/30	Miho Maruyama	Li T, Zhang G, Wu P, Duan L, Li G, Liu Q, Wang J. Dissection of myogenic differentiation signatures in chickens by RNA-Seq analysis. Genes. 2018; 9: 34.
2021/07/16	Machi Yamamoto	Chiappalupi S, Sorci G, Vukasinovic A, Salvadori L, Sagheddu R, Coletti D, Renga G, Romani L, Donato R, Riuzzi F. Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia. J Cachexia Sarcopenia Muscle. 2020; 11: 929-946.
2021/07/09	Rena Ikeda	Zheng Y, Yu W, Li H, Lin H, Chen Z, Chen H, Zhang P, Tian Y, Xu X, Shen Y. CpG oligodeoxynucleotides inhibit the proliferation and osteoclastic differentiation of RAW264.7 cells. RSC Adv. 2020; 10: 14855-14891.
2021/07/02	Machi Yamamoto	山本万智. 筋形成型オリゴ DNA の抗炎症作用の解明. 修士院試 (予演).
2021/06/18	Naoki Nohira	Wang H, Garzon R, Sun H, Ladner KJ, Singh R, Dahlman J, Cheng A, Hall BM, Qualman SJ, Chandler DS, Croce CM, Guttridge DC. NF-κB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell. 2008; 14: 369-381.
2021/06/11	Kamino Morioka	Zhang M, Wang C, Wu J, Ha X, Deng Y, Zhang X, Wang J, Chen K, Feng J, Zhu J, Xie J, Zhang J. The effect and mechanism of KLF7 in the TLR4/NF-κB/IL-6 inflammatory signal pathway of adipocytes. Mediators Inflamm. 2018; 2018: 1756494.
2021/06/04	Mana Miyoshi	Liu J, Li J, Xie C, Xuan L, Tang B. MSCs attenuate hypoxia induced pulmonary hypertension by activating p53 and NF-κB signaling pathway through TNFα secretion. 2020; 532: 400-405.
2021/05/28	Yuma Nihashi	二橋佑磨, 三好愛, 梅澤公二, 下里剛士, 高谷智英. 骨形成型オリゴ DNA は TLR9 非依存的に骨芽細胞の石灰化を促進する. 第21回日本抗加齢医学会 (予演).
	Rena Ikeda	池田玲奈, 二橋佑磨, 梅澤公二, 下里剛士, 高谷智英. 破骨前駆細胞の分化における骨形成型オリゴ DNA の作用. 第21回日本抗加齢医学会 (予演).
	Mana Miyoshi	三好愛, 二橋佑磨, 梅澤公二, 下里剛士, 高谷智英. 血管平滑筋の増殖・分化・石灰化における筋形成型オリゴ DNA の作用. 第21回日本抗加齢医学会 (予演).
	Kamino Morioka	森岡一乃, 三谷塁一, 梅澤公二, 下里剛士, 高谷智英. 筋形成型オリゴ DNA は脂肪細胞分化を抑制する. 第21回日本抗加齢医学会 (予演).
2021/05/21	Yuma Nihashi	Go G, Jeon J, Lee G, Lee JH, Lee SH. Bovine milk extracellular vesicles induce the proliferation and differentiation of osteoblasts and promote osteogenesis in rats. J Food Biochem. 2021; 45: e13705.
2021/05/14	Machi Yamamoto	Ono Y, Sakamoto K. Lipopolysaccharide inhibits myogenic differentiation of C2C12 myoblasts through the Toll-like receptor 4-nuclear factor-κB signaling pathway and myoblast-derived tumor necrosis factor-α. PLoS One. 2017; 12: e0182040.
2021/05/07	Naoki Nohira	Slemmons KK, Crose LE, Riedel S, Sushnitha M, Belyea B, Linardic CM. A novel Notch-YAP circuit drives stemness and tumorigenesis in embryonal rhabdomyosarcoma. Mol Cancer Res. 2017; 15: 1777-1791.
2021/04/23	Kamino Morioka	Matsuo FS, Cavalcanti de Araujo PH, Mota RF, Carvalho AJR, Santos de Queiroz M, Baldo de Almeida B, Ferreira KCOS, Metzner RJM, Ferrari GD, Alberici LC, Osako MK. RANKL induces beige adipocyte differentiation in preadipocytes. Am J Physiol Endocrinol Metab. 2020; 318: E866-E877.
2021/04/16	Mana Miyoshi	Molchadsky A, Shats I, Goldfinger N, Pevsner-Fischer M, Olson M, Rinon A, Trahor E, Lozano G, Zipori D, Sarig R, Rotter V. p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner. PLoS One. 2008; 3: e3707.
2021/04/09	Yuma Nihashi	Melendez J, Sieiro D, Salgado D, Morin V, Dejardin MJ, Zhou C, Mullen AC, Marcelle C. TGFβ signalling acts as a molecular brake of myoblast fusion. Nat Commun. 2021; 12: 749.
2021/02/26	Machi Yamamoto	Hiller M, Geissler M, Janssen G, van Veelen P, Aartsma-Rus A, Spitali P. The mRNA binding proteome of proliferating and differentiated muscle cells. Genomics Proteomics Bioinformatics. In press.
2021/02/19	Miho Maruyama	Espigat-Georger A, Dyachuk V, Chemin C, Emorine L, Merdes A. Nuclear alignment in myotubes requires centrosome proteins recruited by nesprin-1. J Cell Sci. 2016; 129: 4227-4237.
2021/02/12	Naoki Nohira	Liu Z, Zhang X, Lei H, Lam N, Carter S, Yockey O, Xu M, Mendoza A, Hernandez ER, Wei JS, Khan J, Yohe ME, Shern JF, Thiele CJ. CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG. Nat Commun. 2020; 11: 911.
2021/02/05	Mana Miyoshi	三好愛. 血管平滑筋細胞の分化における筋形成型オリゴ DNA の作用. 専攻研究論文発表会 (予演).
	Kamino Morioka	森岡一乃. 脂肪細胞の分化における筋形成型オリゴ DNA の作用. 専攻研究論文発表会 (予演).
2021/01/28	Mina Ishioka	石岡美奈. マウス ES 細胞の心筋分化に伴う遺伝子発現に筋形成型オリゴ DNA が及ぼす作用. 修士論文発表会 (予演).
	Shunichi Nakamura	中村駿一. 筋形成型オリゴ DNA の糖尿病性筋芽細胞への応用. 修士論文発表会 (予演).
2021/01/22	Yuma Nihashi	Muthukuru M, Darveau RP. TLR signaling that induces weak inflammatory response and SHIP1 enhances osteogenic functions. Bone Res. 2014; 2: 14031.
2021/01/13	Kamino Morioka	Zhong W, Zhang Y, Tan W, Zhang J, Liu J, Wang G, Liao J, Liu B, Chen K, Yu B, Deng Y, Zou Y, Pu Y, Liu H. Adipose specific aptamer adipo-8 recognizes and interacts with APMAP to ameliorates fat deposition in vitro and in vivo. Life Sci. 2020; 251: 117609.
2021/01/08	Mana Miyoshi	Kinoshita D, Shishido T, Takahashi T, Yokoyama M, Sugai T, Watanabe K, Tamura H, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Kishida S, Kadomatsu K, Abe JI, Takeishi Y, Konta T, Kubota I, Watanabe M. Growth factor midkine aggravates pulmonary arterial hypertension via surface nucleolin. Sci Rep. 2020; 10: 10345.