Avian stem cell technologies for cellular agriculture
Hiroshi Kagami1, Kie Murai1, Seiya Takizawa1, Hinako Shindo1, Susumu Saito1, Tomohide Takaya1, Kohzy Hiramatsu1, Guojun Sheng2.
- Faculty of Agriculture, Shinshu University, Japan.
- International Research Center for Medical Sciences, Kumamoto University, Japan.
The 7th International Scientific Conference on Cultured Meat (Online), 2021/11/30 (Talk).
Abstract
Avian stem cells derived from stage X chick embryos were found to be pluripotent to differentiate into soma and germline. Genome editing in the stem cells using CRISPR/Cas9 for ovomucoid was successfully conducted. The manipulated stem cells were used to generate germline chimeras. The eggs from the genome-edited chickens could reduce allergy. Avian stem cells have been in vitro cultured for muscle development. These novel technologies should open up new frontier for cellular agriculture in poultry.