Avian stem cell technologies for cellular agriculture

Avian stem cell technologies for cellular agriculture

Hiroshi Kagami1, Kie Murai1, Seiya Takizawa1, Hinako Shindo1, Susumu Saito1, Tomohide Takaya1, Kohzy Hiramatsu1, Guojun Sheng2.

  1. Faculty of Agriculture, Shinshu University, Japan.
  2. International Research Center for Medical Sciences, Kumamoto University, Japan.

The 7th International Scientific Conference on Cultured Meat (Online), 2021/11/30 (Talk).

Abstract

Avian stem cells derived from stage X chick embryos were found to be pluripotent to differentiate into soma and germline. Genome editing in the stem cells using CRISPR/Cas9 for ovomucoid was successfully conducted. The manipulated stem cells were used to generate germline chimeras. The eggs from the genome-edited chickens could reduce allergy. Avian stem cells have been in vitro cultured for muscle development. These novel technologies should open up new frontier for cellular agriculture in poultry.