| Date |
Presenter |
Article |
| 2022/12/16 |
Chihaya Kimura |
Honma M, Ikebuchi Y, Kariya Y, Hayashi M, Hayashi N, Aoki S, Suzuki H. RANKL subcellular trafficking and regulatory mechanisms in osteocytes. J Bone Miner Res. 2013; 28: 1936-1949. |
| 2022/12/09 |
Machi Yamamoto |
Shadle SC, Zhong JW, Campbell AE, Conerly ML, Jagannathan S, Wong CJ, Morello TD, van der Maarel SM, Tapscott SJ. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS Genet. 2017; 13: e1006658. |
| 2022/12/02 |
Kamino Morioka |
Choa R, Tohyama J, Wada S, Meng H, Hu J, Okumura M, May RM, Robertson TF, Pai RL, Nace A, Hopkins C, Jacobsen EA, Haldar M, FitzGerald GA, Behrens EM, Minn AJ, Seale P, Cotsarelis G, Kim B, Seykora JT, Li M, Arany Z, Kambayashi T. Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion. Science. 2021; 373: eabd2893. |
| 2022/11/25 |
Machi Yamamoto |
山本万智. 修士論文中間発表会 (予演). |
| 2022/11/17 |
Mana Miyoshi |
Li B, Zhang Y, Yin R, Zhong W, Chen R, Yan J. Activating CD137 signaling promotes sprouting angiogenesis via increased VEGFA secretion and the VEGFR2/Akt/eNOS pathway. Mediators Inflamm. 2020; 2020: 1649453. |
| 2022/11/11 |
Tomohide Takaya |
Dash S, Trainor PA. Nucleolin loss of function leads to aberrant fibroblast growth factor signaling and craniofacial anomalies. Development. 2022; 149: dev200349. |
| 2022/10/20 |
Machi Yamamoto |
Bosnakovski D, Gearhart MD, Toso EA, Ener ET, Choi SH, Kyba M. Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression. Sci Rep. 2018; 8: 16957. |
| 2022/10/13 |
Kamino Morioka |
Santos EW, Oliveira DC, Hastreiter A, Silva GB, de Oliveira Beltran JS, Rogero MM, Fock RA, Borelli P. Short-term high-fat diet affects macrophages inflammatory response, early signs of a long-term problem. Brz J Pharm Sci. 2019; 55: e17561. |
| 2022/10/07 |
Mana Miyoshi |
Patel S, Mastrogiacomo L, Fulmer M, Shi Y, Werstuck GH. Deletion of macrophage-specific glycogen synthase kinase (GSK)-3α promotes atherosclerotic regression in Ldlr-/- mice. Int J Mol Sci. 2022; 23: 9293. |
| 2022/09/30 |
Tomohide Takaya |
Iturriaga-Goyon E, Vivanco-Rojas O, Magana-Guerrero FS, Buentello-Volante B, Castro-Salas I, Aguayo-Flores J, Gracia-Mora I, Rivera-Huerta M, Sanchez-Bartes F, Garfias Y. AS1411 nucleolin-specific binding aptamers reduce pathological angiogenesis through inhibition of nucleolin phosphorylation. Int J Mol Sci. 2021; 22: 13150. |
| 2022/09/22 |
Machi Yamamoto |
山本万智. 研究紹介. |
| 2022/09/16 |
Kamino Morioka |
森岡一乃. 研究紹介. |
| 2022/09/09 |
Mana Miyoshi |
三好愛. 研究紹介. |
| 2022/09/01 |
Tomohide Takaya |
高谷智英. 研究紹介. |
| 2022/07/29 |
Machi Yamamoto |
Grow EJ, Weaver BD, Smith CM, Guo J, Stein P, Shadle SC, Hendrickson PG, Johnson NE, Butterfield RJ, Menafra R, Kloet SL, van der Maarel SM, Williams CJ, Cairns BR. p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models. Nat Genet. 2021; 53: 1207-1220. |
| 2022/07/22 |
Kamino Morioka |
Wang L, Gao T, Xie Y, Zeng S, Tai C, Feng Y, Shen P, Wang B. A long-term anti-inflammation markedly alleviated high-fat diet-induced obesity by repeated administrations of overexpressing IL10 human umbilical cord-derived mesenchymal stromal cells. Stem Cells Res Ther. 2022; 13: 259. |
| 2022/07/15 |
Mana Miyoshi |
Zeng P, Yang J, Liu L, Yang X, Yao Z, Ma C, Zhu H, Su J, Zhao Q, Feng K, Yang S, Zhu Y, Li X, Wang W, Duan Y, Han J, Chen Y. ERK1/2 inhibition reduces vascular calcification by activating miR-126-3p-DKK1/LRP6 pathway. Theranostics. 2021; 11: 1129-1146. |
| 2022/07/01 |
Yuri Hirabayashi |
平林ゆり. 動物モデルによる筋形成型オリゴ DNA の抗腫瘍効果の検証. 修士院試 (予演). |
| 2022/06/24 |
Machi Yamamoto |
Chau J, Kong X, Nguyen NV, Williams K, Ball M, Tawil R, Kiyono T, Mortazavi A, Yokomori K. Relationship of DUX4 and target gene expression in FSHD myocytes. Hum Mutat. 2021; 42: 421-433. |
| 2022/06/10 |
Mana Miyoshi |
三好愛, 二橋佑磨, 三谷塁一, 梅澤公二, 下里剛士, 高谷智英. 筋形成型オリゴ DNA が血管平滑筋の分化と炎症に及ぼす作用. 第22回日本抗加齢医学会 (予演). |
| Kamino Morioka |
森岡一乃, 三谷塁一, 梅澤公二, 下里剛士, 高谷智英. 筋形成型オリゴ DNA によるヌクレオリン阻害を介した脂肪分化と炎症の抑制. 第22回日本抗加齢医学会 (予演). |
| Machi Yamamoto |
山本万智, 三谷塁一, 高谷智英. ヌクレオリン阻害を介した筋形成型オリゴ DNA の抗炎症作用. 第22回日本抗加齢医学会 (予演). |
| 2022/05/27 |
Kamino Morioka |
Chen Y, Wang J, Wang Y, Wang P, Zhou Z, Wu R, Xu Q, You H, Liu Y, Wang L, Zhou L, Wu Y, Hu L, Liu H, Liu Y. A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex. Nat Commun. 2022; 13: 246. |
| 2022/05/20 |
Mana Miyoshi |
Li CJ, Cheng P, Liang MK, Chen YS, Lu Q, Wang JY, Xia ZY, Zhou HD, Cao X, Xie H, Liao EY, Luo XH. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest. 2015; 125: 1509-1522. |
| 2022/05/13 |
Tomohide Takaya |
Takaya T. myoDN as a potential nucleic acid drug for disease-related muscle wasting. 第7回日本心血管協会学術集会 (予演). |
| 2022/04/26 |
Machi Yamamoto |
Raineri F, Bourgoin-Voillard S, Cossutta M, Habert D, Ponzo M, Houppe C, Vallee B, Boniotto M, Chalabi-Dchar M, Bouvet P, Couvelard A, Cros J, Debesset A, Cohen JL, Courty J, Cascone I. Nucleolin targeting by N6L inhibits Wnt/beta-catenin pathway activation in pancreatic ductal adenocarcinoma. Cancers. 2021; 13: 2986. |
| 2022/04/15 |
Kamino Morioka |
Park JH, Ahn EK, Ko HJ, Hwang MH, Cho YR, Lee DR, Choi BK, Seo DW, Oh JS. Spiraea prunifolia leaves extract inhibits adipogenesis and lipogenesis by promoting β-oxidation in high fat diet-induced obese mice. Biomed Pharmacother. 2022; 149: 112889. |
| 2022/04/08 |
Mana Miyoshi |
Kumar A, Sunita P, Jha S, Pattanayak SP. Daphnetin inhibits TNF-&alpha: and VEGF-induced angiogenesis through inhibition of the IKKs/IκBα/NF-κB, Src/FAK/ERK1/2 and Akt signalling pathways. Clin Exp Pharmacol Physiol. 2016; 43: 939-950. |
| 2022/04/01 |
Tomohide Takaya |
高谷智英. 2022年度の研究計画. |
| 2022/02/03 |
Rena Ikeda |
池田玲奈. 骨形成型オリゴ DNA が破骨前駆細胞に及ぼす影響の解析. 修士論文発表会 (予演). |
| 2022/01/27 |
Naoki Nohira |
野平直樹. 横紋筋肉腫における筋形成型オリゴ DNA の作用. 専攻研究論文発表会 (予演). |
| Machi Yamamoto |
山本万智. 筋形成型オリゴ DNA の抗炎症作用機序. 専攻研究論文発表会 (予演). |
| 2022/01/20 |
Mana Miyoshi |
Kong Y, Liang Q, Chen Y, Yang P, Liu X, Li Y, Feng S, Wu J, Liu W, Tang J, Yu H, Ou JS, Lu L, Yan J. Hyaluronan negatively regulates vascular calcification involving BMP2 signaling. Lab Invest. 2018; 98: 1320-1332. |
| 2022/01/13 |
Kamino Morioka |
Giuliani G, Vumbaca S, Fuoco C, Gargioli C, Giorda E, Massacci G, Palma A, Reggio A, Riccio F, Rosina M, Vinci M, Castagnoli L, Casareni G. SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors. Cell Death Dis. 2021; 12: 122. |
